Description
MUC15 Antibody (PACO14075)
The MUC15 Antibody (PAC014075) is a valuable tool for researchers studying MUC15, a cell surface mucin protein involved in various cellular processes. This polyclonal antibody, generated in rabbits, is highly specific to human samples and is ideal for use in Western blot applications. By binding to the MUC15 protein, this antibody enables accurate detection and analysis in a variety of cell types.MUC15 has been implicated in cell adhesion, signal transduction, and modulation of immune responses, making it a key player in cancer biology and immunology research.
Understanding the functions and regulation of MUC15 is essential for developing potential therapeutic strategies for cancer and inflammatory diseases. The MUC15 Antibody is a reliable tool for investigating the role of MUC15 in cellular pathways and disease progression.
| Antibody Name: | MUC15 Antibody (PACO14075) |
| Antibody SKU: | PACO14075 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human MUC15 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO14075(MUC15 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Human testis tissue, Primary antibody: PACO14075(MUC15 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO14075(MUC15 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most metazoans. Mucin 15 is involved in cell adhesion to the extracellular matrix. It is primarily expressed in prostate, testis, lung, spleen, thymus, ovary, small intestine, colon, bone marrow, lymph node, lung and peripheral blood leukocytes. Mucin 15 is a highly glycosylated protein. |
| Synonyms: | mucin 15, cell surface associated |
| UniProt Protein Function: | MUC15: May play a role in the cell adhesion to the extracellular matrix. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 11p14.3 Cellular Component: Golgi lumen Biological Process: O-glycan processing |
| UniProt Code: | Q8N387 |
| NCBI GenInfo Identifier: | 84028223 |
| NCBI Gene ID: | 143662 |
| NCBI Accession: | Q8N387.2 |
| UniProt Secondary Accession: | Q8N387,Q6UWS3, Q8IXI8, Q8WW41, B3KY00, E9PII6, F8W945 |
| UniProt Related Accession: | Q8N387 |
| Molecular Weight: | 30,762 Da |
| NCBI Full Name: | Mucin-15 |
| NCBI Synonym Full Names: | mucin 15, cell surface associated |
| NCBI Official Symbol: | MUC15Â Â |
| NCBI Official Synonym Symbols: | PAS3; MUC-15; PASIIIÂ Â |
| NCBI Protein Information: | mucin-15 |
| UniProt Protein Name: | Mucin-15 |
| Protein Family: | Mucin |
| UniProt Gene Name: | MUC15Â Â |
| UniProt Entry Name: | MUC15_HUMAN |
