The MXD1 Antibody (CAB3613) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the MXD1 protein, this antibody allows for the detection and analysis of MXD1 expression in a variety of cell types, making it an essential component for studies in molecular biology and cancer research.MXD1, also known as Max Dimerization Protein 1, plays a crucial role in controlling cell growth and differentiation by regulating gene transcription. Its involvement in cellular processes makes it a key player in understanding diseases such as cancer, where dysregulation of cell cycle control can lead to uncontrolled cell proliferation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
MXD1 Antibody
SKU:
CAB3613
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MAD, MAD1, BHLHC58, MXD1
Positive Sample:
MCF7, Rat testis
Cellular Localization:
Nucleus.
Calculated MW:
25kDa
Observed MW:
22kDa
This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method
Affinity purification
Gene ID
4084
RRID
AB_2765180
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MXD1 Rabbit pAb (CAB3613) at 1:800 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
