The MYO10 Antibody (CAB12471) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to MYO10 in human samples and is validated for use in Western blot and immunofluorescence applications.MYO10 is a unique myosin that is involved in the movement of organelles and vesicles along actin filaments within cells. Its abnormalities have been linked to various diseases, including cancer and neurodevelopmental disorders. By targeting MYO10 with this antibody, researchers can investigate its role in cellular processes and disease pathogenesis with high specificity and sensitivity.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
MYO10 Antibody
SKU:
CAB12471
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis.
Purification Method
Affinity purification
Gene ID
4651
RRID
AB_2759316
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MYO10 Rabbit pAb (CAB12471) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 20s.
Immunofluorescence analysis of U2OS cells using MYO10 Rabbit pAb (CAB12471) at dilution of 1:350. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of HeLa cells using MYO10 Rabbit pAb (CAB12471) at dilution of 1:350. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.