The N Antibody (PACO34226) is a highly specific and sensitive tool for studying the protein N, which is a key player in cellular pathways related to immune response and inflammation. This polyclonal antibody is produced using high-quality materials and has been extensively validated for use in various experimental applications, including Western blotting and immunofluorescence.The N protein is implicated in various cellular processes, including viral replication and host immune evasion, making it a valuable target for research in virology and immunology.
By using the N Antibody, researchers can gain insights into the mechanisms underlying viral pathogenesis and immune response modulation, providing opportunities for the development of novel antiviral therapies and vaccines.Overall, the N Antibody (PACO34226) is a versatile research tool that can significantly contribute to our understanding of viral infections, immune response pathways, and the development of targeted therapies for infectious diseases.
Antibody Name:
N Antibody (PACO34226)
Antibody SKU:
PACO34226
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Rabies virus
Immunogen:
Recombinant Rabies virus Nucleoprotein protein (1-450AA)
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases
Synonyms:
Nucleoprotein (NP) (Nucleocapsid protein) (Protein N), N
UniProt Protein Function:
Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it's own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases ().
