The NAPB Antibody (CAB18223) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to NAPB, it enables the detection and analysis of this important protein in various cell types, making it ideal for studies in neuroscience and neurology.NAPB, also known as SNAP receptor, plays a crucial role in the release of neurotransmitters and the communication between neurons in the brain. Dysregulation of NAPB has been implicated in various neurological disorders, including epilepsy, Alzheimer's disease, and Parkinson's disease.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
NAPB Antibody
SKU:
CAB18223
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SNAPB, DEE107, SNAP-BETA, NAPB
Positive Sample:
Mouse brain, Mouse eye, Rat brain
Cellular Localization:
Membrane, Peripheral Membrane Protein.
Calculated MW:
34kDa
Observed MW:
37kDa
This gene encodes a member of the soluble N-ethyl-maleimide-sensitive fusion attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. This gene encodes the SNAP beta isoform which has been shown to be preferentially expressed in brain tissue. The encoded protein also interacts with the GluR2 α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit C-terminus and may play a role as a chaperone in the molecular processing of the AMPA receptor.
Purification Method
Affinity purification
Gene ID
63908
RRID
AB_2861999
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NAPB Rabbit pAb (CAB18223) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
