The NBPF4 Polyclonal Antibody (PACO03533) is a valuable tool for researchers studying NBPF4, a protein involved in neurodevelopment and neuron function. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it ideal for experiments such as Western blotting. By binding to NBPF4, this antibody enables the detection and analysis of the protein in various cell types, offering insights into its role in neurobiology and potential implications in neurological disorders.NBPF4, a member of the neuroblastoma breakpoint family of proteins, is known to play a role in neural development and function. Research suggests that NBPF4 may be involved in processes such as cell differentiation, neuronal migration, and synaptic signaling, making it a focus of interest in neuroscience studies.
Understanding the function and regulation of NBPF4 can provide valuable insights into neurological conditions and potential therapeutic targets for neurodegenerative diseases.Overall, the NBPF4 Polyclonal Antibody (PACO03533) is a reliable tool for researchers interested in furthering our understanding of NBPF4 and its implications in neurobiology. Its specificity and sensitivity make it a valuable asset for studies aiming to unravel the complexities of neural development and potential applications in neurological disorders.
Antibody Name:
NBPF4 Antibody
Antibody SKU:
PACO03533
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human NBPF4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
NBPF4; Neuroblastoma breakpoint family member 4
UniProt Protein Function:
MiscellaneousEncoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.
UniProt Protein Details:
NCBI Summary:
This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Mar 2013]
