The NBPf7 Polyclonal Antibody (PACO01142) is a valuable tool for researchers studying NBPF7, a protein associated with neuroblastoma during neurogenesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. It specifically targets the NBPF7 protein, allowing for precise detection and analysis in various cell types.NBPF7, also known as neuroblastoma breakpoint family member 7, is involved in neural development and has been implicated in neuroblastoma tumorigenesis.
By understanding the function of NBPF7, researchers can gain insights into the mechanisms underlying neuroblastoma and potentially identify new therapeutic targets for this pediatric cancer. The NBPf7 Polyclonal Antibody is a valuable tool for investigating the role of NBPF7 in neurogenesis and neuroblastoma pathogenesis.
Antibody Name:
NBPF7 Antibody
Antibody SKU:
PACO01142
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human NBPF7.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
NBPF7; Putative neuroblastoma breakpoint family member 7
UniProt Protein Function:
NBPF7: Belongs to the NBPF familyChromosomal Location of Human Ortholog: 1p12Cellular Component: cytoplasm
UniProt Protein Details:
NCBI Summary:
This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Mar 2013]
