The NCLN Antibody (PACO04789) is a high-quality polyclonal antibody designed for research involving NCLN, a crucial protein involved in various cellular processes. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it an excellent tool for Western blot applications.NCLN is known to play a role in lipid metabolism and has been implicated in various diseases, including neurodegenerative disorders and metabolic syndromes. The NCLN Antibody enables the detection and analysis of NCLN protein in different cell types, making it ideal for studies in cell biology, metabolism, and disease mechanisms.
With its high specificity and sensitivity, the NCLN Antibody is a valuable tool for researchers looking to elucidate the function of NCLN and its implications in various cellular processes and disease states. Its application extends to a wide range of research areas, making it a versatile tool for scientists studying lipid metabolism, neurodegeneration, and metabolic diseases.
Antibody Name:
NCLN Antibody
Antibody SKU:
PACO04789
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the C-terminal region of human Nicalin.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
NCLN; Nicalin; Nicastrin-like protein
UniProt Protein Function:
NCLN: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. Belongs to the nicastrin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 19p13.3Cellular Component: endoplasmic reticulum membrane; membrane; integral to membraneMolecular Function: protein bindingBiological Process: regulation of signal transduction
