The NDUFC1 Polyclonal Antibody (PAC00407) is a valuable tool for research involving NDUFC1, a key subunit of mitochondrial complex I involved in oxidative phosphorylation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications such as Western blot and immunofluorescence. By binding specifically to NDUFC1, researchers can accurately detect and study this protein in different cell types, making it ideal for investigations in mitochondrial biology and bioenergetics.NDUFC1 is essential for the proper functioning of complex I, the largest enzyme complex in the mitochondrial electron transport chain.
Mutations or dysregulation of NDUFC1 have been linked to various mitochondrial disorders and metabolic diseases. Therefore, studying the role and regulation of NDUFC1 is crucial for understanding mitochondrial function and its implications in human health and disease.Utilizing the NDUFC1 Polyclonal Antibody in your research can provide valuable insights into the mechanisms of oxidative phosphorylation, mitochondrial disorders, and potential therapeutic targets for metabolic conditions. Its specificity and sensitivity make it a reliable tool for scientists studying mitochondrial biology and bioenergetics.
Antibody Name:
NDUFC1 Antibody
Antibody SKU:
PACO04407
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human NDUFC1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
UniProt Protein Details:
NCBI Summary:
The encoded protein is a subunit of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
