The NECAB1 Polyclonal Antibody (CAB15883) is a valuable tool for research involving NECAB1, a calcium-binding protein that plays a key role in regulating neurotransmitter release in the brain. This antibody, generated in rabbits, is highly specific to human NECAB1 protein and has been validated for use in various applications, including Western blotting and immunofluorescence.NECAB1 is known to modulate synaptic transmission and plasticity, making it a crucial player in neuronal communication and synaptic function. Its dysregulation has been implicated in neurological disorders such as Alzheimer's disease and schizophrenia, highlighting the importance of studying its function in both normal and disease states.
By using the NECAB1 Polyclonal Antibody, researchers can investigate the expression and localization of NECAB1 in different cell types and tissues, providing valuable insights into its role in neurobiology. This antibody is a valuable asset for studies aiming to understand the molecular mechanisms underlying neurotransmission and synaptic plasticity, ultimately contributing to the development of novel therapeutic strategies for neurological disorders.
Product Name:
NECAB1 Rabbit Polyclonal Antibody
SKU:
CAB15883
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human NECAB1 (NP_071746.1).
Enables identical protein binding activity. Predicted to be involved in regulation of amyloid precursor protein biosynthetic process. Predicted to act upstream of or within blastocyst hatching. Located in cytosol and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
64168
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from LO2 cells, using NECAB1 Rabbit pAb (CAB15883) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
