The NHP2-like Protein 1 Polyclonal Antibody (CAB5926) is a valuable tool for researchers studying NHP2-like Protein 1, a key player in RNA processing and telomere maintenance. This antibody, produced in rabbits, has high specificity for human samples and is ideal for use in Western blot applications. By binding to the NHP2-like Protein 1, researchers can detect and analyze its expression in various cell types, making it essential for investigations in molecular biology and cancer research.NHP2-like Protein 1 is essential for proper ribosome biogenesis and telomerase function, making it a crucial component in cellular processes such as protein synthesis and chromosome stability.
Dysregulation of NHP2-like Protein 1 has been implicated in diseases like cancer and genetic disorders, highlighting its importance as a potential therapeutic target. By studying NHP2-like Protein 1 with this antibody, researchers can gain valuable insights into its role in disease pathogenesis and develop targeted interventions for treating associated conditions.
Product Name:
NHP2L1 Rabbit Polyclonal Antibody
SKU:
CAB5926
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human NHP2L1 (NP_004999.1).
Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4809
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NHP2L1 antibody (CAB5926) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
