The NLGN4Y Polyclonal Antibody (CAB4513) is a valuable tool for researchers studying NLGN4Y, a cell adhesion molecule essential for synaptic function in the brain. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to the NLGN4Y protein, enabling precise detection and analysis in various biological samples.NLGN4Y is a key player in synaptic transmission and has been linked to neurodevelopmental disorders such as autism spectrum disorder.
Research on NLGN4Y is crucial for understanding the molecular mechanisms underlying neurological conditions and for developing targeted therapies. The NLGN4Y Polyclonal Antibody is an essential tool for investigators studying synaptic function, neurodevelopment, and neurological disorders.
Product Name:
NLGN4Y Rabbit Polyclonal Antibody
SKU:
CAB4513
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 122-256 of human NLGN4Y (NP_001157710.1).
Cell junction, Cell membrane, Single-pass type I membrane protein, postsynaptic cell membrane, postsynaptic density, synapse.
Calculated MW:
92kDa
Observed MW:
100kDa
This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
22829
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using NLGN4Y Rabbit pAb (CAB4513) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
