The NLN Antibody (CAB13112) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for NLN and is suitable for use in Western blotting and immunohistochemistry applications.NLN, also known as neurolysin, is a zinc-dependent metallopeptidase that plays a crucial role in maintaining cellular homeostasis and proper functioning of the nervous system. Dysregulation of NLN has been linked to neurodegenerative disorders, cancer, and other diseases, highlighting its importance as a potential therapeutic target.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
NLN Antibody
SKU:
CAB13112
Size:
20μL, 100μL
Reactivity:
Human, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MEP, MOP, AGTBP, EP24.16, NLN
Positive Sample:
HeLa
Cellular Localization:
Cytoplasm, Mitochondrion Intermembrane Space.
Calculated MW:
81kDa
Observed MW:
70kDa
This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.
Purification Method
Affinity purification
Gene ID
57486
RRID
AB_2759961
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from HeLa cells, using NLN Rabbit pAb (CAB13112) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
