The NLRC5 Polyclonal Antibody (CAB16710) is a valuable tool for research involving NLRC5, a protein belonging to the NLR family which plays a crucial role in immune regulation and inflammation. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to NLRC5, this antibody allows for accurate detection and analysis of the protein in a variety of cell types, making it ideal for studies in immunology and cancer research.
NLRC5 is known for its involvement in immune response modulation and its ability to regulate inflammatory pathways. Its role in immune homeostasis makes it a key player in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By understanding the functions of NLRC5, researchers can gain insight into new therapeutic targets for treating these diseases and modulating immune responses effectively.
Product Name:
NLRC5 Rabbit Polyclonal Antibody
SKU:
CAB16710
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human NLRC5 (NP_115582.4).
This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.
Purification Method:
Affinity purification
Gene ID:
84166
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse lung, using NLRC5 antibody (CAB16710) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
