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NME1/NM23A Polyclonal Antibody (CAB21512)

SKU:
CAB21512
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IF
$155 - $431
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:NME1/NM23A Polyclonal Antibody
SKU:CAB21512
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 10-110 of human NME1/NM23A (NP_000260.1).
Sequence:AIKP DGVQ RGLV GEII KRFE QKGF RLVG LKFM QASE DLLK EHYV DLKD RPFF AGLV KYMH SGPV VAMV WEGL NVVK TGRV MLGE TNPA DSKP GTIR GDFC I
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1; NME1/NM23A
Positive Sample:A549,MCF7,HeLa,Hep G2
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:17kDa
Observed MW:Refer to figures

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Purification Method:Affinity purification
Gene ID:4830
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using NME1/NM23A Rabbit pAb (CAB21512).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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