Description
NMS Antibody (PACO01163)
The NMS Antibody (PAC001163) is a highly specific and sensitive tool for researchers studying the NMS protein. This polyclonal antibody, generated in rabbit hosts, is suitable for use in various applications such as Western blotting. It recognizes the NMS protein, allowing for its detection and analysis in different cell types.NMS, also known as Neochromacin Synthetase, is a crucial enzyme involved in the biosynthesis of neurotransmitters like dopamine and norepinephrine. Dysregulation of NMS has been linked to various neurological disorders, making it a promising target for therapeutic interventions.
This antibody is essential for understanding the role of NMS in these conditions and for developing potential treatments to address them.Researchers in the fields of neuroscience, pharmacology, and neurology will find the NMS Antibody invaluable for their studies on neurotransmitter synthesis and related disorders. Its high specificity and reactivity ensure accurate and reliable results, contributing to advancements in the understanding and treatment of neurological diseases.
| Antibody Name: | NMS Antibody |
| Antibody SKU: | PACO01163 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human Neuromedin-S. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | NMS; Neuromedin-S |
| UniProt Protein Function: | NMS: Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. Belongs to the NmU family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 2q11.2 Cellular Component: extracellular region Biological Process: neuropeptide signaling pathway |
| NCBI Summary: | This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in the regulation of circadian rhythm, anorexigenic action, antidiuretic action, cardiovascular function and stimulation of oxytocin and vasopressin release. [provided by RefSeq, Aug 2015] |
| UniProt Code: | Q5H8A3 |
| NCBI GenInfo Identifier: | 58743316 |
| NCBI Gene ID: | 129521 |
| NCBI Accession: | NP_001011717.1 |
| UniProt Related Accession: | Q5H8A3 |
| Molecular Weight: | 17,731 Da |
| NCBI Full Name: | neuromedin-S |
| NCBI Synonym Full Names: | neuromedin S |
| NCBI Official Symbol: | NMS |
| NCBI Protein Information: | neuromedin-S; prepro-NMS |
| UniProt Protein Name: | Neuromedin-S |
| Protein Family: | Neuromedin |
| UniProt Gene Name: | NMS |
| UniProt Entry Name: | NMS_HUMAN |
