The NPDC1 Polyclonal Antibody (PAC022458) is a valuable tool for research involving NPDC1, a protein associated with neuronal cell development and function. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including Western blotting. By specifically binding to the NPDC1 protein, this antibody enables accurate detection and analysis in a range of cell types, making it ideal for studies in neuroscience and neurodegenerative diseases.
NPDC1, also known as neuronal pentraxin domain-containing protein 1, is involved in synaptic plasticity and has been implicated in conditions such as Alzheimer's disease and schizophrenia. Understanding the role of NPDC1 in neuronal function is crucial for unraveling the mechanisms underlying these disorders and developing targeted therapies. The NPDC1 Polyclonal Antibody provides researchers with a powerful tool for investigating the function and regulation of NPDC1 in both normal and disease states.
Antibody Name:
NPDC1 Antibody (PACO22458)
Antibody SKU:
PACO22458
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human NPDC1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from LOVO cells and HepG2 cells, using NPDC1 antibody.
Background:
Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation By similarity.
Synonyms:
neural proliferation differentiation and control protein 1 precursor; NPDC-1;
UniProt Protein Function:
NPDC1: Suppresses oncogenic transformation in neural and non- neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation. Belongs to the NPDC1/cab-1 family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 9q34.3Cellular Component: integral to membrane
