Description
NPTX1 Antibody (PACO10912)
The NPTX1 Polyclonal Antibody (PACO10912) is a valuable tool for researchers studying NPTX1, a protein involved in synaptic plasticity and cognitive function. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the NPTX1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in neuroscience and neurodegenerative diseases.NPTX1, also known as neuronal pentraxin 1, is known to play a crucial role in synaptic transmission and plasticity, making it a key player in learning and memory processes.
Dysregulation of NPTX1 has been associated with various neurological disorders, such as Alzheimer's disease and schizophrenia, highlighting the importance of studying this protein in the context of brain function and dysfunction. By understanding the function of NPTX1, researchers may uncover new insights into the mechanisms underlying these conditions and identify potential therapeutic targets.
| Antibody Name: | NPTX1 Antibody (PACO10912) |
| Antibody SKU: | PACO10912 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human NPTX1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | neuronal pentraxin I;NPTX1;DKFZp686J2446;MGC105123;NP1 ; |
| UniProt Protein Function: | NPTX1: May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 17q25.3 Biological Process: central nervous system development; synaptic transmission; transport |
| NCBI Summary: | NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15818 |
| NCBI GenInfo Identifier: | 77416871 |
| NCBI Gene ID: | 4884 |
| NCBI Accession: | Q15818.2 |
| UniProt Secondary Accession: | Q15818,Q5FWE6, B3KXH3, |
| UniProt Related Accession: | Q15818 |
| Molecular Weight: | 47,122 Da |
| NCBI Full Name: | Neuronal pentraxin-1 |
| NCBI Synonym Full Names: | neuronal pentraxin 1 |
| NCBI Official Symbol: | NPTX1Â Â |
| NCBI Official Synonym Symbols: | NP1Â Â |
| NCBI Protein Information: | neuronal pentraxin-1 |
| UniProt Protein Name: | Neuronal pentraxin-1 |
| UniProt Synonym Protein Names: | Neuronal pentraxin I; NP-I |
| Protein Family: | Neuronal pentraxin |
| UniProt Gene Name: | NPTX1Â Â |
| UniProt Entry Name: | NPTX1_HUMAN |
