The NRIP3 Polyclonal Antibody (PAC016793) is a vital tool for researchers studying NRIP3, a key player in inflammatory responses and cellular metabolism. This antibody, produced in rabbits, exhibits high reactivity specifically with human samples and is validated for use in Western blot applications. By binding to the NRIP3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for studies in immunology, metabolism, and inflammation research.
NRIP3, also known as nuclear receptor interacting protein 3, is involved in regulating gene expression, metabolic pathways, and inflammation responses. Its critical role in these cellular processes makes NRIP3 a relevant target for investigating diseases such as cancer, metabolic disorders, and inflammatory conditions. Understanding the function and regulation of NRIP3 is essential for the development of potential therapeutic interventions that target these pathways and processes.
Antibody Name:
NRIP3 Antibody (PACO16793)
Antibody SKU:
PACO16793
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human NRIP3
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16793(NRIP3 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200).
Background:
NRIP3 (nuclear receptor interacting protein 3), also known as C11orf14 or NY-SAR-105, is a 241 amino acid, protein that is encoded by a gene which maps to human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks.
Synonyms:
nuclear receptor interacting protein 3
UniProt Protein Function:
NRIP3: Chromosomal Location of Human Ortholog: 11p15.3Molecular Function: aspartic-type endopeptidase activity; protein bindingBiological Process: proteolysis
