The NUP58 Polyclonal Antibody (CAB17598) is a valuable tool for researchers studying NUP58, a nuclear pore protein involved in nucleocytoplasmic transport. This rabbit-derived antibody is highly specific to human samples and is validated for use in Western blotting applications. By binding to the NUP58 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for research in molecular biology and cell biology.NUP58 is a key player in the transport of macromolecules between the nucleus and cytoplasm, playing a crucial role in gene expression and cellular communication.
By studying the function of NUP58, researchers can gain insights into fundamental cellular processes and potentially uncover new therapeutic targets for diseases related to nucleocytoplasmic transport dysregulation. The NUP58 Polyclonal Antibody is a powerful tool for unraveling the complexities of this essential protein and advancing scientific knowledge in the field of cell biology.
Product Name:
NUP58 Rabbit Polyclonal Antibody
SKU:
CAB17598
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human NUP58 (NP_054808.1).
This gene encodes a member of the nucleoporin family that shares 87% sequence identity with rat nucleoporin p58. The protein is localized to the nuclear rim and is a component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
9818
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat liver, using NUP58 Rabbit pAb (CAB17598) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
