The OR2T11 Antibody (PAC002469) is a high-quality polyclonal antibody designed for research involving OR2T11, a protein expressed in olfactory receptor neurons with a potential role in odor detection. The antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in various applications such as Western blotting.OR2T11, a member of the olfactory receptor family, is involved in the detection and transduction of odorant signals in the olfactory system. Research on OR2T11 can provide insights into the molecular mechanisms underlying olfaction and help in understanding how different odorants are detected and processed by the olfactory system.
The OR2T11 Antibody is a valuable tool for scientists studying olfaction, sensory perception, and neurological disorders related to smell dysfunction. By targeting OR2T11, researchers can explore the specific functions and signaling pathways associated with this olfactory receptor, leading to a better understanding of olfaction and potential therapeutic interventions for olfactory-related conditions.
Antibody Name:
OR2T11 Antibody
Antibody SKU:
PACO02469
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 2T11.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR2T11: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1Chromosomal Location of Human Ortholog: 1q44Cellular Component: integral to membrane; plasma membraneMolecular Function: olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
