The OR4A15 Polyclonal Antibody (PAC00127) is a valuable tool for researchers studying OR4A15, a member of the olfactory receptor (OR) family involved in the detection of odor molecules. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in applications such as immunohistochemistry and flow cytometry.OR4A15 is a G-protein coupled receptor expressed in olfactory sensory neurons, playing a key role in the sense of smell. Research on OR4A15 includes investigations into how olfactory receptors contribute to our perception of odors and how variations in these receptors can impact individual differences in smell perception.
By using the OR4A15 Polyclonal Antibody, researchers can better understand the function and regulation of OR4A15 in olfactory processes, providing valuable insights into the complexities of human olfaction. This antibody is an essential tool for studies aimed at unraveling the molecular mechanisms underlying our sense of smell.
Antibody Name:
OR4A15 Antibody
Antibody SKU:
PACO01227
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4A15.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4A15: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; Receptor, misc.; GPCR, family 1Chromosomal Location of Human Ortholog: 11q11Cellular Component: integral to membrane; plasma membraneMolecular Function: transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
