The OR4C12 Monoclonal Antibody (PAC001229) is a vital tool for researchers studying OR4C12, a member of the olfactory receptor gene family involved in detecting odor molecules. This antibody, produced through hybridoma technology, shows high specificity for OR4C12 in human samples and is validated for use in immunocytochemistry and flow cytometry applications. By binding to the OR4C12 protein, this antibody enables accurate detection and analysis of OR4C12 expression in various cell types, making it ideal for studies in sensory perception and olfactory function.
OR4C12 is a key player in olfactory sensation, playing a crucial role in the detection and discrimination of a wide range of odorants. Understanding the function of OR4C12 is essential for unraveling the complexities of the olfactory system and its implications for behaviors such as food preferences, mating behaviors, and disease detection. This antibody provides researchers with a powerful tool to explore the role of OR4C12 in olfaction, opening up new avenues for research into sensory biology and neurological disorders related to olfactory dysfunction.
Antibody Name:
OR4C12 Antibody
Antibody SKU:
PACO01229
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4C12.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4C12: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 11p11.12Cellular Component: integral to membrane; plasma membraneMolecular Function: transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
