The OR4C16 Polyclonal Antibody (PACO02690) is a crucial tool for researchers studying the OR4C16 gene, a member of the olfactory receptor (OR) gene family involved in detecting odors. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting OR4C16 in human samples, making it ideal for use in applications such as Western blot and immunohistochemistry.The OR4C16 gene plays a significant role in olfaction, the sense of smell, by encoding a protein that binds to specific odor molecules and triggers signals to the brain for processing. Research on OR genes like OR4C16 is essential for understanding how the brain interprets and responds to different smells, and how this process influences behavior and physiology.
By using the OR4C16 Polyclonal Antibody, researchers can explore the expression patterns and function of the OR4C16 gene in various tissues and cell types, advancing our understanding of olfactory perception and potentially offering insights into neurological disorders or conditions related to olfactory dysfunction. This antibody is a valuable tool for studies in neuroscience, sensory biology, and drug development targeting the olfactory system.
Antibody Name:
OR4C16 Antibody
Antibody SKU:
PACO02690
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4C16.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4C16: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 11q11Cellular Component: integral to membrane; plasma membraneMolecular Function: transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
