The OR4D1 Polyclonal Antibody (PACO01233) is a valuable tool for researchers studying OR4D1, a member of the olfactory receptor family involved in the detection of odors. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the OR4D1 protein, researchers can effectively study its expression and function in various cell types, making it ideal for investigations in sensory biology and olfactory research.OR4D1 is a crucial player in the olfactory system, responsible for detecting specific odor molecules and relaying this information to the brain for interpretation.
Understanding the mechanisms behind OR4D1 activation and signaling is essential for gaining insight into how the sense of smell works and how it influences behaviors and physiological responses. Research on OR4D1 may also have implications for developing new therapies for smell-related disorders and enhancing our understanding of sensory processing in general.
Antibody Name:
OR4D1 Antibody
Antibody SKU:
PACO01233
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4D1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4D1: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 17q23.2Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
