The OR4K2 Polyclonal Antibody (PAC004202) is a valuable tool for researchers studying olfactory receptor 4K2, a protein involved in the detection of specific odors. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding to the OR4K2 protein, this antibody allows for the detection and analysis of olfactory receptor 4K2 in different cell types, making it ideal for investigations in sensory biology and smell perception research.Olfactory receptor 4K2, a member of the olfactory receptor gene family, plays a crucial role in detecting and distinguishing particular odors in the environment.
Understanding the function and regulation of OR4K2 can provide insights into how the olfactory system works and how animals perceive their surroundings through scent. Researchers studying olfaction, sensory perception, and the role of olfactory receptors in behavior can benefit from using this antibody to study the expression and localization of OR4K2 in various tissues and cell types.
Antibody Name:
OR4K2 Antibody
Antibody SKU:
PACO04202
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4K2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4K2: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 14q11.2Cellular Component: integral to membrane; plasma membraneMolecular Function: transmembrane receptor activityBiological Process: detection of chemical stimulus involved in sensory perception; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
