The OR4K3 Polyclonal Antibody (PACO03923) is a valuable tool for researchers studying OR4K3, a member of the olfactory receptor family involved in detecting odors. This antibody, produced in rabbits, is highly specific for human OR4K3 and has been validated for use in various applications, including Western blotting.OR4K3 is a critical player in the olfactory system, responsible for detecting specific odor molecules and triggering a physiological response. By targeting OR4K3 with this antibody, researchers can study its expression and function in different tissues and cell types, shedding light on the mechanisms of olfaction and odor recognition.
The ability to detect and analyze OR4K3 using this antibody is essential for unraveling the complexities of the olfactory system and understanding how the brain processes and interprets odor signals. With its high specificity and sensitivity, the OR4K3 Polyclonal Antibody is a valuable tool for advancing research in sensory perception and olfaction.
Antibody Name:
OR4K3 Antibody
Antibody SKU:
PACO03923
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 4K3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR4K3: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCRChromosomal Location of Human Ortholog: 14q11.2Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]
