The OR5M1/ OR5M10 Polyclonal Antibody (PAC004198) is a valuable tool for researchers studying olfactory receptors. These receptors are important in the sense of smell and play a role in detecting various odors. The antibody, produced in rabbits, is highly specific and reacts with human samples, making it ideal for use in research on olfactory function and disorders.This antibody binds to the OR5M1 and OR5M10 proteins, allowing for their detection and analysis in different cell types.
Its validation for use in Western blot applications ensures reliable results for researchers studying olfactory receptors and their functions. By understanding the role of these receptors, researchers can gain insights into how our sense of smell works and potentially develop new therapies for olfactory-related conditions.
Antibody Name:
OR5M1/OR5M10 Antibody
Antibody SKU:
PACO04198
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 5M1/5M10.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR5M1: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 11q12.1Cellular Component: plasma membraneMolecular Function: odorant binding; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
