The OR8K3 Polyclonal Antibody (PACO02692) is a valuable tool for researchers studying OR8K3, a member of the olfactory receptor family involved in odor detection. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the OR8K3 protein, this antibody enables the detection and analysis of OR8K3 in a variety of cell types, making it ideal for studies in neuroscience and sensory perception research.
OR8K3, a key player in olfactory signal transduction, is essential for the detection of specific odors and plays a critical role in the sense of smell. Research on OR8K3 can provide insights into how the olfactory system functions and how different odors are perceived. Further understanding of OR8K3's function may lead to advancements in various fields, including fragrance development, food industry, and neurological disorders related to smell perception.
Antibody Name:
OR8K3 Antibody
Antibody SKU:
PACO02692
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human Olfactory receptor 8K3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR8K3: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCRChromosomal Location of Human Ortholog: 11q12.1Cellular Component: plasma membraneMolecular Function: odorant binding; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
