The OXCT1 Polyclonal Antibody (CAB21844) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the OXCT1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in metabolism, mitochondrial function, and related diseases.OXCT1 plays a vital role in the breakdown of fatty acids for energy production, making it essential for normal metabolic function.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
OXCT1 Polyclonal Antibody
SKU:
CAB21844
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
OXCT, SCOT, OXCT1
Positive Sample:
293T, Mouse kidney
Cellular Localization:
Mitochondrion Matrix.
Calculated MW:
56kDa
Observed MW:
56kDa
This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
Purification Method
Affinity purification
Gene ID
5019
RRID
AB_3711663
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using OXCT1 Rabbit pAb (CAB21844) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates / proteins: 25 μg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
