The OXER1 Polyclonal Antibody (PACO11034) is a valuable tool for researchers studying the OXER1 receptor, a protein involved in the regulation of inflammation and immune responses. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the OXER1 receptor, this antibody allows for accurate detection and analysis of OXER1 expression in a variety of cell types, making it an ideal choice for studies in immunology and inflammation research.
The OXER1 receptor, also known as GPR32, plays a crucial role in mediating the body's response to inflammation and oxidative stress. Its involvement in these processes makes it a promising target for research into inflammatory conditions such as cardiovascular disease, asthma, and neurodegenerative disorders. By understanding the function of the OXER1 receptor, researchers can gain valuable insights into potential therapeutic interventions for these conditions, ultimately improving patient outcomes.
OXER1: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1Chromosomal Location of Human Ortholog: 2p21Cellular Component: integral to membrane; plasma membraneMolecular Function: 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding; G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; regulation of cAMP biosynthetic process
