The P2RY13 Polyclonal Antibody (PACO4619) is a valuable tool for researchers studying the P2RY13 receptor, a G protein-coupled receptor involved in various physiological processes. This antibody, developed using rabbits, exhibits high specificity and sensitivity for detecting P2RY13 in human samples, making it suitable for use in Western blotting and other immunoassays.P2RY13, also known as purinergic receptor P2Y13, is known for its role in mediating responses to extracellular nucleotides, particularly in the central nervous system. Its functions in neurotransmission and immune responses make it an intriguing target for investigation in neurobiology, inflammation, and related fields.
The ability to detect and study P2RY13 using this antibody opens up opportunities for advancing research into the mechanisms underlying these processes.Researchers interested in exploring the functions and signaling pathways of P2RY13 can benefit from the specificity and reliability of this antibody, which enables precise detection and analysis of P2RY13 expression in various cell types and tissues. By gaining a deeper understanding of P2RY13 biology, scientists may uncover new insights with implications for drug discovery, therapeutic development, and disease mechanisms.
Antibody Name:
P2RY13 Antibody
Antibody SKU:
PACO04619
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human, Rat
Immunogen:
synthesized peptide derived from the Internal region of human P2RY13.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
P2RY13: Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1Chromosomal Location of Human Ortholog: 3q24Cellular Component: endoplasmic reticulum; integral to plasma membrane; plasma membraneMolecular Function: purinergic nucleotide receptor activity, G-protein coupledBiological Process: negative regulation of adenylate cyclase activity
UniProt Protein Details:
NCBI Summary:
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008]
