The PACO16827 Polyclonal Antibody is a valuable tool for researchers studying CD300A, a cell surface molecule crucial for immune regulation. This antibody, developed in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the CD300A protein, this antibody allows for the detection and analysis of this important molecule in various cell types, making it an ideal choice for studies in immunology and cancer research.
CD300A, also known as an immune inhibitory receptor, plays a vital role in immune homeostasis by controlling inflammation and inhibiting allergic reactions. Its role in modulating immune responses has significant implications for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By studying CD300A activity, researchers can uncover new insights that may lead to the development of targeted therapies for these conditions.
Antibody Name:
PAGE5 Antibody (PACO16827)
Antibody SKU:
PACO16827
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:300
Species Reactivity:
Human
Immunogen:
Fusion protein of human PAGE5
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16827(PAGE5 Antibody) at dilution 1/55, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene is a member of the GAGE family, which is expressed in a variety of tumors and in some fetal and reproductive tissues. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. It may also belong to a family of CT (cancer-testis) antigens. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants have not been determined.
Synonyms:
P antigen family, member 5 (prostate associated)
UniProt Protein Function:
PAGE5: a member of the GAGE family, which is expressed in a variety of tumors and in some fetal and reproductive tissues. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. It may also belong to a family of CT (cancer-testis) antigens. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants have not been determined. [provided by RefSeq, Jul 2008]Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xp11.21Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This gene is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues. The encoded protein may protect cells from programmed cell death. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jan 2015]
