The PAIP1 Antibody (CAB6042) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific and reactive towards human samples, making it ideal for use in Western blot applications. By binding to the PAIP1 protein, this antibody enables researchers to detect and analyze PAIP1 expression in various cell types, offering insights into its functions in cellular processes.PAIP1 plays a crucial role in the regulation of protein synthesis by facilitating the interaction between poly(A)-binding protein (PABP) and eukaryotic translation initiation factor 4G (eIF4G). This interaction is essential for the translation of mRNA into proteins, highlighting the significance of PAIP1 in cellular function and homeostasis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PAIP1 Antibody
SKU:
CAB6042
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Purification Method
Affinity purification
Gene ID
10605
RRID
AB_2766725
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PAIP1 Rabbit pAb (CAB6042) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
