The PAN2 Polyclonal Antibody (CAB15373) is a powerful tool for researchers studying the PAN2 protein, which is involved in RNA metabolism and mRNA surveillance pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to PAN2, researchers can accurately detect and analyze this protein in a variety of cell types, making it ideal for investigations in molecular biology and gene regulation.PAN2 is a key player in mRNA degradation processes and is essential for maintaining cellular RNA homeostasis.
Dysregulation of PAN2 activity has been linked to various diseases, including neurological disorders and cancer. By studying the function of PAN2, researchers can gain valuable insights into RNA metabolism and potentially identify novel therapeutic targets for treating these conditions. The PAN2 Polyclonal Antibody is a valuable tool for exploring the role of PAN2 in health and disease, advancing our understanding of RNA biology.
Product Name:
PAN2 Rabbit Polyclonal Antibody
SKU:
CAB15373
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human PAN2 (NP_001120932.1).
This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
9924
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PAN2 Rabbit pAb (CAB15373) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 15s.
