The PANK3 Polyclonal Antibody (PACO11066) is a high-quality research tool designed for studying PANK3, an enzyme involved in the biosynthesis of coenzyme A. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the PANK3 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal tool for researchers in the fields of biochemistry and molecular biology.PANK3 is a key enzyme in the CoA biosynthetic pathway, playing a crucial role in cellular metabolism and energy production. Dysregulation of PANK3 has been implicated in various metabolic disorders, making it a promising target for therapeutic interventions.
Research into the function and regulation of PANK3 is essential for understanding its role in diseases such as diabetes, obesity, and neurodegenerative disorders.By using the PANK3 Polyclonal Antibody (PACO11066), researchers can gain valuable insights into the molecular mechanisms underlying CoA biosynthesis and its implications for human health. This antibody is an essential tool for investigating the role of PANK3 in metabolic pathways and developing targeted therapies for metabolic disorders.
PANK3: Plays a role in the physiological regulation of the intracellular CoA concentration. Belongs to the type II pantothenate kinase family.Protein type: EC 2.7.1.33; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; Kinase, otherChromosomal Location of Human Ortholog: 5q34
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver. [provided by RefSeq, Jul 2008]
