The PDCD1LG2 Polyclonal Antibody (PACO11133) is a powerful tool for researchers studying the PD-L2 protein, a key regulator of immune responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the PD-L2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential resource for studies in immunology and cancer research.PD-L2, also known as programmed death ligand 2, plays a critical role in immune checkpoint regulation by interacting with the PD-1 receptor and modulating T cell responses.
Its involvement in immune evasion and tolerance makes it a promising target for understanding diseases such as cancer, chronic infections, and autoimmune disorders. Investigating the functions of PD-L2 is essential for developing novel immunotherapies that enhance or suppress immune responses in the context of these diseases.
PDCL2: May play a role in germ cell maturation. Belongs to the phosducin family.Chromosomal Location of Human Ortholog: 4q12Cellular Component: cytoplasmMolecular Function: queuine tRNA-ribosyltransferase activityBiological Process: queuosine biosynthetic process
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]
