The PDGFR-L Polyclonal Antibody (CAB9169) is a valuable tool for researchers studying PDGFR-L, a receptor protein involved in cell communication and growth regulation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the PDGFR-L protein, researchers can accurately detect and analyze its expression in various cell types, providing insights into its role in cellular processes.PDGFR-L, also known as platelet-derived growth factor receptor-like protein, is a key player in signaling pathways that control cell proliferation, differentiation, and survival.
Dysregulation of PDGFR-L activity has been implicated in diseases like cancer, fibrosis, and vascular disorders, making it a promising target for therapeutic development. By studying PDGFR-L using this polyclonal antibody, researchers can uncover valuable information that may lead to the identification of new treatment strategies for these conditions.
Product Name:
PDGFRL Rabbit Polyclonal Antibody
SKU:
CAB9169
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 15-205 of human PDGFRL (NP_006198.1).
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
Purification Method:
Affinity purification
Gene ID:
5157
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PDGFRL antibody (CAB9169) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
