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PE Anti-Human CD8a Antibody [HIT8a] (AGEL3392)

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SKU AGEL3392
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, k
Clone HIT8a
Conjugation PE
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Description

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PE Anti-Human CD8a Antibody [HIT8a]

The PE-anti-Human CD8a Antibody (HIT8a) offered by AssayGenie is a powerful tool for immunology research, particularly focusing on CD8a, a crucial cell surface marker involved in T cell recognition and function. This antibody is specifically designed for use in flow cytometry applications, providing a reliable and sensitive method for detecting and analyzing CD8a expression on human cells.Targeting the CD8a protein, this antibody enables precise identification and characterization of CD8a-positive cell populations in various biological samples. Its high specificity and sensitivity make it an ideal choice for studies related to immune responses, infectious diseases, and cancer immunology.

The PE-conjugated format allows for easy integration into multicolor flow cytometry panels, facilitating comprehensive immune profiling and cell subset analysis.With its validated performance in flow cytometry, the PE-anti-Human CD8a Antibody (HIT8a) from AssayGenie is a valuable asset for researchers exploring the role of CD8a-positive T cells in immunity, inflammation, and disease pathogenesis. Trust in this antibody to enhance your research endeavors and advance your understanding of cellular immune responses in health and disease.

Product Title:PE Anti-Human CD8a Antibody [HIT8a]
SKU:AGEL3392
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIT8a
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T8;Leu2;MAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01732
Gene ID:925
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

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