The PE Anti-Mouse H-2 Antibody (M1/42) is a vital tool for researchers studying immune responses and histocompatibility in mouse models. This monoclonal antibody, clone M1/42, is highly specific for the H-2 complex, a major histocompatibility complex (MHC) in mice. Utilizing a phycoerythrin (PE) conjugation, this antibody allows for easy detection and analysis of H-2 expression in various cell types, particularly in flow cytometry applications.The H-2 complex plays a crucial role in antigen presentation and immune recognition, making it essential for understanding immune responses and immunological processes in mice.
By targeting the H-2 antigen with high specificity, researchers can investigate immune cell interactions, T cell activation, and immune tolerance mechanisms in experimental settings. The PE Anti-Mouse H-2 Antibody (M1/42) serves as a valuable tool for elucidating the complex immune pathways and mechanisms involved in mouse models, aiding in the advancement of immunology and transplantation research.
Product Title:
PE Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL2411
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.
![PE Anti-Mouse H-2 Antibody [M1/42] (AGEL2411)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/1280x1280/products/229137/605341/pe-anti-mouse-h-2-antibody-m142-agel2411__61903.1706890125.jpg?c=2?imbypass=on "PE Anti-Mouse H-2 Antibody [M1/42] (AGEL2411)")
![PE Anti-Mouse H-2 Antibody [M1/42] (AGEL2411)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/608x608/products/229137/605341/pe-anti-mouse-h-2-antibody-m142-agel2411__61903.1706890125.jpg?c=2 "PE Anti-Mouse H-2 Antibody [M1/42] (AGEL2411)")
![PE Anti-Mouse H-2 Antibody [M1/42] (AGEL2419)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/229145/605089/pe-anti-mouse-h-2-antibody-m142-agel2419__78404.1706889294.jpg?c=2 "PE Anti-Mouse H-2 Antibody [M1/42] (AGEL2419)")
![PE/Cyanine7 Anti-Mouse H-2 Antibody [M1/42] (AGEL3157)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/230031/605127/pecyanine7-anti-mouse-h-2-antibody-m142__28653.1706889418.jpg?c=2 "PE/Cyanine7 Anti-Mouse H-2 Antibody [M1/42] (AGEL3157)")
![PE/Cyanine5 Anti-Mouse H-2 Antibody [M1/42] (AGEL2413)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/229139/602751/pecyanine5-anti-mouse-h-2-antibody-m142-agel2413__82033.1706285699.jpg?c=2 "PE/Cyanine5 Anti-Mouse H-2 Antibody [M1/42] (AGEL2413)")
![PE/Cyanine5.5 Anti-Mouse H-2 Antibody [M1/42] (AGEL2414)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/229140/602774/pecyanine5.5-anti-mouse-h-2-antibody-m142-agel2414__65956.1706285803.jpg?c=2 "PE/Cyanine5.5 Anti-Mouse H-2 Antibody [M1/42] (AGEL2414)")
![PE/Cyanine5 Anti-Mouse H-2 Antibody [M1/42] (AGEL2421)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/229147/602072/pecyanine5-anti-mouse-h-2-antibody-m142-agel2421__18927.1706283543.jpg?c=2 "PE/Cyanine5 Anti-Mouse H-2 Antibody [M1/42] (AGEL2421)")