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PE Anti-Rat CD45 Antibody [OX-1] (AGEL2450)

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SKU AGEL2450
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Rat
Host Species Mouse
Isotype Mouse IgG1, κ
Clone OX-1
Conjugation PE
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Description

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PE Anti-Rat CD45 Antibody [OX-1]

The PE Anti-Rat CD45 Antibody (OX-1) from Assay Genie (Catalog No. AGEL2450) is a highly specific and sensitive antibody designed for research involving CD45, a cell surface protein marker that plays a crucial role in immune cell activation and differentiation. This antibody, generated using OX-1 hybridoma cells, is optimized for use in flow cytometry applications, allowing for precise identification and characterization of rat immune cell populations.CD45, also known as leukocyte common antigen, is a key regulator of immune cell signaling and activation. It is essential for proper immune responses and is widely used as a marker for various immune cell types, including T cells, B cells, and myeloid cells.

The PE Anti-Rat CD45 Antibody (OX-1) specifically recognizes rat CD45, enabling researchers to accurately analyze immune cell subsets and investigate their functions in a variety of experimental settings.This high-quality antibody from Assay Genie offers researchers a reliable tool for studying immune cell populations in rat models, making it ideal for immunology research, inflammation studies, and drug discovery efforts targeting immune system modulation. With its consistent performance and specificity, the PE Anti-Rat CD45 Antibody (OX-1) is a valuable asset for scientists looking to advance their understanding of immune cell biology and develop novel therapeutic strategies.

Product Title:PE Anti-Rat CD45 Antibody [OX-1]
SKU:AGEL2450
Size:25µg, 100µg
Clone No:OX-1
Synonyms:Receptor-type tyrosine-protein phosphatase C;Leukocyte common antigen; LCA; T200; Ly-5;Ptprc;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04157
Gene ID:19265
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

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