The PE-Cyanine5 Anti-Mouse H-2 Antibody (M1/42) (AGEL2413) is a valuable tool for researchers studying immune responses in mice. This antibody, specifically designed for use in flow cytometry applications, targets the H-2 antigen on mouse cells with high specificity and sensitivity. The H-2 antigen plays a crucial role in the immune system, involved in antigen presentation and immune response regulation. By using this antibody, researchers can easily detect and analyze H-2 expression on different cell types, providing valuable insights into immune function and immune-mediated diseases in mouse models.
With its reliable performance and specificity, the PE-Cyanine5 Anti-Mouse H-2 Antibody (M1/42) (AGEL2413) is an essential tool for immunology research, particularly in studies focused on understanding immune responses and developing therapies for conditions such as cancer, autoimmune disorders, and infectious diseases in mouse models.
Product Title:
PE/Cyanine5 Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL2413
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.
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