The PE Cyanine5 Anti-Mouse H-2 Antibody (M1/42) is a crucial tool for researchers studying immune responses in mouse models. This antibody, designed for flow cytometry applications, specifically targets the H-2 antigens on mouse cells, allowing for precise identification and analysis of immune cell populations.H-2 antigens play a vital role in the immune system by presenting antigens to T cells and regulating immune responses. The PE Cyanine5 Anti-Mouse H-2 Antibody (M1/42) enables researchers to investigate the expression of H-2 antigens on different immune cell subsets, aiding in the understanding of immune function and response in various experimental contexts.
With its high specificity and sensitivity, this antibody is an essential tool for immunologists, oncologists, and researchers studying immunology, cancer immunotherapy, and autoimmune diseases in mouse models. By providing valuable insights into immune cell behavior and function, the PE Cyanine5 Anti-Mouse H-2 Antibody (M1/42) supports advancements in the fields of immunology and biomedical research.
Product Title:
PE/Cyanine5 Anti-Mouse H-2 Antibody [M1/42]
SKU:
AGEL2421
Size:
25µg, 100µg
Clone No:
M1/42
Synonyms:
Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
111364
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.
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