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PE/Cyanine5 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL2222)

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SKU AGEL2222
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone RB6-8C5
Conjugation PE/Cyanine5
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Description

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PE/Cyanine5 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The PE-Cyanine5 Anti-Mouse Ly-6G, Ly-6C (GR-1) Antibody (RB6-8C5) is a vital tool for researchers studying the immune system in mice. This antibody specifically targets Ly-6G and Ly-6C surface markers, which are commonly used to identify and characterize different subsets of immune cells, particularly myeloid-derived suppressor cells.With its high specificity and sensitivity, the PE-Cyanine5 Anti-Mouse Ly-6G, Ly-6C (GR-1) Antibody (RB6-8C5) enables precise detection and analysis of these important cell populations in various experimental settings. Whether investigating immune responses, inflammation, infection, or cancer in mouse models, this antibody provides reliable results in flow cytometry, immunofluorescence, and other experimental techniques.

The Ly-6G and Ly-6C antigens are crucial for understanding the dynamics of the immune system, including inflammatory processes and immune cell regulation. By using this antibody, researchers can gain insights into the roles of these markers in health and disease, paving the way for advancements in immunology, oncology, and other fields where immune cell characterization is essential for progress and discovery.

Product Title:PE/Cyanine5 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL2222
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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