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PE/Cyanine7 Anti-Mouse CD90.2 Antibody [30H12] (AGEL2185)

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SKU AGEL2185
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone 30H12
Conjugation PE/Cyanine7
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Description

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PE/Cyanine7 Anti-Mouse CD90.2 Antibody [30H12]

The PE-Cyanine7 Anti-Mouse CD90.2 Antibody (30-H12) from Assay Genie is a vital tool for researchers studying CD90.2, a cell surface marker known as Thy1.2, which is commonly used to identify mouse T cells, hematopoietic stem cells, and certain fibroblast populations. The antibody, conjugated with PE-Cyanine7, offers high specificity and sensitivity in flow cytometry experiments, enabling precise detection and characterization of CD90.2-expressing cells.CD90.2, a key regulator of cell adhesion, migration, and signaling pathways, plays a crucial role in immune responses and tissue regeneration. Its expression pattern and functional significance make it a valuable marker for identifying and isolating specific cell populations in immunology and stem cell research.

By targeting CD90.2 with this antibody, researchers can gain insight into the roles of T cells, stem cells, and fibroblasts in various physiological and pathological processes.The PE-Cyanine7 Anti-Mouse CD90.2 Antibody (30-H12) is meticulously validated for use in flow cytometry applications, providing reliable and reproducible results for in-depth cellular analysis. It opens up new avenues for investigating the function and behavior of CD90.2-positive cells in immune responses, stem cell biology, and tissue repair mechanisms, making it an invaluable tool for understanding the intricacies of mouse cell populations in diverse experimental settings.

Product Title:PE/Cyanine7 Anti-Mouse CD90.2 Antibody [30H12]
SKU:AGEL2185
Size:50 Tests, 100 Tests, 200 Tests
Clone No:30H12
Synonyms:Thy-1.2 membrane glycoprotein;Thy1.2;Thy-1.2 antigen;CD90.2;Thy-1.2;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:21838
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.

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