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PE/Cyanine7 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL2223)

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SKU AGEL2223
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2b, κ
Clone RB6-8C5
Conjugation PE/Cyanine7
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Description

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PE/Cyanine7 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The PE-Cyanine7 Anti-Mouse LY-6G/LY-6C (GR-1) Antibody (RB6-8C5) offered by Assay Genie is a vital tool for researchers studying immune cells in mice. This antibody, designed for flow cytometry applications, specifically targets the LY-6G and LY-6C antigens, commonly used to identify granulocytes and monocytes in murine samples. With its high reactivity and specificity, this antibody enables precise detection and differentiation of these cell populations in various experimental settings.LY-6G and LY-6C are important markers in immunology, playing crucial roles in the immune response, inflammation, and infection.

By using the PE-Cyanine7 Anti-Mouse LY-6G/LY-6C (GR-1) Antibody (RB6-8C5), researchers can delve deeper into the function and behavior of these specific cell types, aiding in studies related to immunity, inflammation, and disease pathogenesis. This antibody is a valuable asset for those investigating conditions such as infections, autoimmune disorders, and inflammatory diseases in murine models, providing insights that can lead to advancements in therapeutic strategies and interventions.

Product Title:PE/Cyanine7 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL2223
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Cyanine7 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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