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PE/GenieFluor 594 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL3254)

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SKU:
AGEL3254
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgM, k
Clone:
RA3.3A 1/6.1
Conjugation:
PE/AF594
$227 - $515

Description

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PE/GenieFluor 594 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The PE GenieFluor 594 Anti-Mouse CD45R/B220 Antibody (RA3-6B2) (AGEL3254) is a highly specific antibody designed for the detection of CD45R/B220 cell surface marker in mouse samples. This antibody, labeled with PE GenieFluor 594, is ideal for flow cytometry applications due to its bright and stable fluorescence signal. It recognizes the CD45R/B220 protein, allowing for precise identification and characterization of B cells in various tissues and cell populations.CD45R, also known as B220, is a well-established marker for B cell lineage in mice. Its expression is crucial for the identification and classification of B cells in immunological studies.

The PE GenieFluor 594 Anti-Mouse CD45R/B220 Antibody provides researchers with a reliable tool to study B cell development, activation, and function with high specificity and sensitivity.With its enhanced fluorescent properties, this antibody enables accurate and efficient analysis of B cell populations in a variety of research settings, including immunology, oncology, and autoimmune disease studies. By targeting the CD45R/B220 marker, researchers can gain valuable insights into B cell biology and immune responses, advancing our understanding of immune system function and disease pathology.

Product Title:PE/GenieFluor 594 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL3254
Size:25µg, 100µg
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Isotype Control:PE/Genie Fluor 594 Rat IgM, κ Isotype Control[RTK2118]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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