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PE/GenieFluor 594 Anti-Mouse CD80 Antibody [16-10A1] (AGEL3173)

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SKU AGEL3173
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Armenian Hamster
Isotype Armenian Hamster IgG
Clone 16-10A1
Conjugation PE/AF594
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Description

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PE/GenieFluor 594 Anti-Mouse CD80 Antibody [16-10A1]

The PE-GenieFluor 594 Anti-Mouse CD80 Antibody (16-10A1) from Assay Genie (AGEL3173) is an essential tool for researchers studying the immune system and inflammatory responses in mice. This high-quality antibody is specifically designed to target the CD80 protein, a critical co-stimulatory molecule involved in T cell activation.With its PE-GenieFluor 594 conjugation, this antibody offers strong fluorescent signal detection for flow cytometry and immunofluorescence applications. Its specificity for mouse CD80 ensures accurate and reliable results in various experimental settings, including in vitro and in vivo studies.By targeting CD80, researchers can gain insights into the complex interactions between immune cells and their role in mounting effective immune responses.

This antibody enables precise detection and analysis of CD80 expression, facilitating in-depth investigations into immune cell activation, regulation, and dysfunction.Overall, the PE-GenieFluor 594 Anti-Mouse CD80 Antibody (16-10A1) is a valuable tool for immunologists, cell biologists, and researchers interested in understanding the intricacies of immune regulation and inflammatory processes in mouse models. Its high sensitivity and specificity make it a key component in advancing our knowledge of immune responses and potential therapeutic targets for immune-related diseases.

Product Title:PE/GenieFluor 594 Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL3173
Size:25µg, 100µg
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE/Genie Fluor 594 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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