The Peroxiredoxin 2 (PRDX2) Polyclonal Antibody (CAB21814) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PRDX2 protein, this antibody enables the detection and analysis of PRDX2 in a variety of cell types, making it an excellent choice for studies in oxidative stress, aging, and disease research.PRDX2 is a member of the peroxiredoxin family, which are essential for maintaining cellular redox balance and protecting against oxidative damage. As a key player in the antioxidant defense system, PRDX2 is involved in regulating multiple cellular processes, including cell proliferation, apoptosis, and signal transduction pathways.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Peroxiredoxin 2 (PRDX2) Polyclonal Antibody
SKU:
CAB21814
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Hep G2, Mouse brain, Rat brain, Rat spleen, Rat heart
Cellular Localization:
Cytoplasm.
Calculated MW:
22kDa
Observed MW:
Refertofigures
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
Purification Method
Affinity purification
Gene ID
7001
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Peroxiredoxin 2 (PRDX2) Rabbit pAb (CAB21814) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Western blot analysis of various lysates using Peroxiredoxin 2 (PRDX2) Rabbit pAb (CAB21814) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Immunofluorescence analysis of HeLa cells using Peroxiredoxin 2 (PRDX2) Rabbit pAb (CAB21814) at dilution of 1:200 (40x lens).Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
