The PGBD5 Antibody (PAC018488) is a valuable tool for researchers studying PGBD5, a protein with a potential role in immune regulation and genetic recombination. This polyclonal antibody, produced in rabbits, is highly specific to human samples and is validated for use in various applications, including Western blotting and immunohistochemistry.PGBD5 is a transposase-like protein that has been implicated in DNA transposition and regulation of gene expression. Its involvement in these processes suggests potential implications in cancer biology, developmental biology, and epigenetic regulation.
The ability to detect and study PGBD5 with this antibody opens up new avenues for exploring its functions in different cell types and biological contexts.Research into PGBD5 is still ongoing, and the development of tools like the PGBD5 Antibody is essential for furthering our understanding of this protein's role in health and disease. With its high specificity and reliability, this antibody is a valuable asset for scientists investigating the molecular mechanisms underlying immune responses and genetic regulation.
Antibody Name:
PGBD5 Antibody (PACO18488)
Antibody SKU:
PACO18488
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:15-1:50
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human PGBD5
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18488(PGBD5 Antibody) at dilution 1/10, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families.
Synonyms:
piggyBac transposable element derived 5
UniProt Protein Function:
Subcellular location: Membrane; Single-pass membrane protein Potential. Sequence caution: The sequence CAI13996.2 differs from that shown. Reason: Erroneous gene model prediction.
UniProt Protein Details:
NCBI Summary:
The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. [provided by RefSeq, May 2010]
